Type 2 Diabetes

Type 2 diabetes, formerly called adult-onset or noninsulindependent diabetes, is the most common form of diabetes. People can develop type 2 diabetes at any age, even during childhood. This form of diabetes usually begins with insulin resistance, a condition in which fat, muscle, and liver cells do not use insulin properly. At first, the pancreas keeps up with the added demand by producing more insulin. In time, however, it loses the ability to secrete enough insulin in response to meals. People who are overweight and inactive are more likely to develop type 2 diabetes. Treatment includes taking diabetes medicines, making wise food choices, exercising regularly, controlling blood pressure and cholesterol, and taking aspirin daily—for some.

What is Type 2 Diabetes?

Type 2 diabetes is a common metabolic condition that develops when the body fails to produce enough insulin or when insulin fails to work properly, which is referred to as insulin resistance. Insulin is the hormone that stimulates cells to uptake glucose from the blood to use for energy.

Diabetes Mellitus Type 2 Pathophysiology

Type 2 Diabetes Symptoms

Type 2 Diabetes Diagnosis

Type 2 Diabetes Screening and Prevention

Type 2 Diabetes Treatment

Living With Type 2 Diabetes

Vitamin D and Type 2 Diabetes

Is a Plant-Based Diet Good for Type 2 Diabetes?

Are Low Carbohydrate Diets Good for Type 2 Diabetes?

What is Insulin Resistance?

Insulin Resistance Pathophysiology

See more featured articles »

Causes of Insulin Resistance

Insulin Resistance Treatment

Insulin Resistance Diagnosis

Insulin Resistance Symptoms

Insulin Resistance and Parkinson's Disease

Does the Keto Diet Increase the Risk of Diabetes?

The Risks of Prediabetes

What is Diabetes?

Fibromyalgia and Diabetes

Diabetes in Men versus Women

Insulin Medication

Latest Type 2 Diabetes News and Research

Meta-analysis reports global prevalence of MAFLD of 38.8% in adults

Non-alcoholic fatty liver disease (NAFLD) is a common condition that affects up to 30% of adults in the general population.

18 Aug 2023

Male diabetics more likely to have lower limb amputation

New research to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Hamburg, Germany (2-6 October) shows that among people with type 1 and type 2 diabetes, being divorced is associated with a two-thirds higher risk of lower limb amputation (LLA) (amputations below the knee level) compared with being married, and being male is associated with a 57% higher risk of LLA compared with being female. The study is by Dr Stefan Jansson, Örebro University, Örebro, Sweden, and colleagues.

18 Aug 2023

Medications for chronic diseases can impair thermoregulation, especially in hot weather

Medications to treat various chronic diseases may hinder the body’s ability to lose heat and regulate its core temperature to optimal levels.

17 Aug 2023

Obesity impairs brain's ability to learn associations

To control our behavior, the brain must be able to form associations. This involves, for example, associating a neutral external stimulus with a consequence following the stimulus (e.g., the hotplate glows red - you can burn your hand).

17 Aug 2023

Exposure to interpersonal violence throughout childhood or adulthood increases risk of diabetes

According to the results of a new study in the American Journal of Preventive Medicine, published by Elsevier, exposure to interpersonal violence throughout childhood or adulthood increases an individual's chance of developing adult-onset diabetes by more than 20%.

17 Aug 2023

Metabolic changes after gastric bypass surgery reverse within one year

A new study from Lund University in Sweden raises questions about the efficacy of bariatric operations involving gastric bypass.

17 Aug 2023

Researchers receive DoD grant to target chemotherapy resistance in pancreatic cancer

Researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have been awarded a grant from the U.S. Department of Defense (DoD)'s Congressionally Directed Medical Research Program to target chemotherapy resistance in pancreatic cancer.

17 Aug 2023

Brief nurse-delivered sleep restriction therapy in primary care is clinically effective for insomnia disorder, safe, and likely to be cost-effective

Researchers compare the cost-effectiveness and clinical impact of nurse-delivered sleep restriction therapy with sleep hygiene for insomnia treatment.

17 Aug 2023

Study: 93 million U.S. adults may benefit from semaglutide medication

Researchers from the University of California, Irvine have just published a study that projects 93 million U.S. adults that are overweight and obese may be suitable for the 2.4 mg dosage of semaglutide, a weight loss medication known under the brand name Wegovy.

16 Aug 2023

Study shows arterial stiffness as a novel cause of premature heart damage among adolescents

Arterial stiffness is a novel cause of premature heart damage among adolescents, according to a new follow-up study.

16 Aug 2023

Study shows COVID-19 vaccination reduces, but does not entirely ameliorate, excess diabetes incidence after COVID-19

Researchers investigate the effect of COVID-19 and its vaccination on the incidence and persistence of type 2 diabetes.

15 Aug 2023

Newly discovered protein kinase shows promise for establishing future obesity and diabetes treatments

Researchers used genetically modified animal models to investigate the role of the newly discovered Traf2- and NCK-interacting protein kinase (TNIK) in obesity and metabolic dysfunction.

15 Aug 2023

The impact of oat consumption on the gut microbiota

The relationship between the gut microbiome and oat consumption.

15 Aug 2023

Genetic determinants of retinol circulation and their impact on health

The genetic architecture of circulating retinol.

15 Aug 2023

Can fasting benefit individuals with diabetes?

Fasting and its effect on diabetes.

15 Aug 2023

Intensive lifestyle intervention linked to increased employment for people with type 2 diabetes

USC Schaeffer Center and University of Minnesota researchers found that study participants without a college degree had even larger employment gains from lifestyle changes recommended by specialists.

14 Aug 2023

Is 'time in range' the preferred glycemic metric to evaluate cognitive fuction in diabetics?

Researchers examine the association between time in range, a glycemic metric, and cognitive impairment in patients with type 2 diabetes

14 Aug 2023

Study examines the relationship between consumption of fatty acids and diabetic retinopathy

Researchers examined the relationship between dietary fatty acid (FA) intake and diabetic retinopathy (DR).

14 Aug 2023

Glucokinase activators induce hepatic lipid accumulation in mice with high-fat diet

The researchers demonstrated that glucokinase activation was effective in lowering blood glucose in mice with high-fat diet-induced obesity, while it potentially raised the risk of increasing hepatic lipid accumulation that triggered the PERK-UPR pathway.

11 Aug 2023

Personalized exercise testing may be more effective for fat loss

The best heart rate for burning fat differs for each individual and often does not align with the "fat burning zone" on commercial exercise machines, Icahn School of Medicine at Mount Sinai researchers report.

11 Aug 2023

Type 2 Diabetes

Overview

Feature Articles

Type 2 Diabetes Screening and Prevention

Type 2 Diabetes Treatment

Living With Type 2 Diabetes

Vitamin D and Type 2 Diabetes

Is a Plant-Based Diet Good for Type 2 Diabetes?

Are Low Carbohydrate Diets Good for Type 2 Diabetes?

What is Insulin Resistance?

Insulin Resistance Pathophysiology

Causes of Insulin Resistance

Insulin Resistance Treatment

Insulin Resistance Diagnosis

Insulin Resistance Symptoms

Insulin Resistance and Parkinson's Disease

Does the Keto Diet Increase the Risk of Diabetes?

The Risks of Prediabetes

What is Diabetes?

Fibromyalgia and Diabetes

Diabetes in Men versus Women

Insulin Medication

Latest Type 2 Diabetes News and Research

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